吴燕,女,中共党员,副教授,理学博士(博士后),重庆市“巴渝学者.青年学者”,重庆市涪陵区科研项目评审专家。
主要从事生物传感器的研究,构建了一系列生物传感器用于肿瘤标志物与环境污染物的高灵敏检测。近年来,主持国家自然科学基金青年项目1项、重庆市自然科学基金2项、重庆市教委科学技术研究项目2项、湖南省创新平台与人才计划项目1项、湖南省自然科学基金1项等项目;以骨干人员参研重庆市自然科学基金3项。以第一作者或通讯作者在Analytical Chemistry、Biosensors and Bioelectronics、Green Chemistry、Chinese Chemical Letters和Sensors and Actuators B: Chemical等国际权威刊物上发表SCI论文20余篇,其中ESI高被引论文2篇,授权发明专利3项,并担任Biosensors and Bioelectronics、Sensors and Actuators B: Chemical和Talanta等国际知名期刊审稿人。2022年入选“重庆市巴渝学者.青年学者”人才计划、获“科研创新先进个人”、“优秀共产党员”、“优秀毕业论文指导教师”、“最美志愿者”等荣誉称号。
参加工作至今,积极开展教学教研工作,主要承担《仪器分析》《仪器分析实验》《分析化学实验》和《化工专业英语》等课程的教学工作,并受到了学生的一致好评;主持教育部产学合作协同育人项目1项、校级教改项目1项、校级课程思政示范课程建设项目1项,发表多篇教改论文;获2023年校级精品课堂教学比赛二等奖、2023年校级教师教学创新大赛二等奖;先后指导学生立项校级大学生创新创业训练项目2项。
联系邮箱:wyan2018@163.com
学习及工作经历:
2019.01至今,长江师范学院化学化工学院,副教授
2023.09-2024.08,重庆万凯新材料科技有限公司,科技副总监(挂职)
2021.07-2023.11,南华大学衡阳医学院,博士后
2017.07-2018.12,长江师范学院化学化工学院,讲师
2011.09-2017.06,湖南大学化学化工学院,分析化学博士(硕博连读)
2007.09-2011.06,衡阳师范学院化学与材料科学学院,化学生物学学士
主持的主要科研项目(不超过20项):
(1)主持国家自然科学基金课题“基于催化发卡组装信号放大技术的比率型SERS传感器用于microRNA检测及拉曼成像研究”(No. 201804011), 2019.01-2021.12.
(2)主持重庆市科委自然科学基金课题“基于三维DNA步行器的超灵敏SERS传感器构建及其对癌胚抗原的检测研究”(No. CSTB2023NSCQ-MSX0229), 2023.08-2026.07.
(3)主持重庆市科委自然科学基金课题“基于比率型SERS传感器对三峡库区水环境中重金属离子的检测研究”(No. cstc2018jcyjAX0721), 2018.08-2021.07.
(4)主持重庆市教委课题“基于深度学习的SERS技术在早期肺癌无创诊断中的应用” (No. KJQN202301412), 2023.08-2026.08.
(5)主持重庆市教委课题“基于单层MoS2纳米片的SERS传感器对microRNA的检测应用研究”(No. KJQN201801404), 2018.08-2021.07.
(6)主持湖南省创新平台与人才计划项目“高灵敏SERS探针用于细胞内生物分子的快速检测”(No. 2021RC2085), 2021.07-2023.09.
(7)主持湖南省自然科学基金项目“基于三维DNA Walker的SERS生物传感器构建及其对癌胚抗原的超灵敏检测研究”(No. 2022JJ40364), 2022.01-2024.12.
(8)主持长江师范学院青年科研人才成长支持计划,2018年.
(9)主持光电传感与生命分析教育部重点实验室(青岛科技大学)开放课题“基于三维DNA步行器的SERS传感器构建及在肺癌早期诊断中的研究”(No. M2024-8), 2024.01-2025.12.
代表性论文、专利、专著、奖励(不超过20篇):
(1)Yan Wu*, Jing Liu, Rong Xu, Jing Li, Cuicui Fu, Wenbing Shi, Jinyang Chen*. Recent advances in ratiometric surface-enhanced Raman spectroscopy sensing strategies. Microchemical Journal 2024, 199, 110127.
(2)Yan Wu*, Rongnan Yi, Honghui Zang, Jing Li, Rong Xu, Fang Zhao, Junli Wang, Cuicui Fu, Jinyang Chen*. Ratiometric SERS Sensor with One Signal Probe for Ultrasensitive and Quantitative Monitoring of Serum Xanthine. Analyst 2023, 148, 5707-5713.
(3)Yan Wu*, Jinyang Chen, Weimin He. Surface-enhanced Raman spectroscopy biosensor based on silver nanoparticles@metal-organic frameworks with peroxidase-mimicking activities for ultrasensitive monitoring of blood cholesterol. Sensors and Actuators B: Chemical 2022, 365, 131939.
(4)Yan Wu, Jinyang Chen, Jing Ning, Xue Jiang, Jie Deng, Yu Deng, Rui Xu, Weimin He*. Electrochemical multicomponent synthesis of 4-selanylpyrazoles under catalyst- and chemical oxidant-free conditions. Green Chemistry 2021, 23, 3950-3954.
(5)Yan Wu*, Cuicui Fu, Wenbing Shi, Jinyang Chen*. Recent advances in catalytic hairpin assembly signal amplification-based sensing strategies for microRNA detection. Talanta 2021, 235, 122735.
(6)Yan Wu, Jin-Yang Chen, Hong-Rui Liao, Xiao-Rong Shu, Li-Lan Duan, Xiao-Feng Yang, Wei-Min He*. Electrochemical transient iodination and coupling for selenylated 4-anilinocoumarin synthesis. Green Synthesis and Catalysis 2021, 2, 233-236.
(7)Yan Wu*, Cuicui Fu, Jie Xiang, Yulian Cao, Yu Deng, Rui Xu, Huan Zhang, Wenbing Shi. “Signal-on” SERS sensing platform for highly sensitive and selective Pb2+ detection based on catalytic hairpin assembly. Analytica Chimica Acta 2020, 1127, 106-113.
(8)Yan Wu, Yingwu Lin, Weimin He*. Microwave-assisted 6π-electrocyclization in water. Chinese Chemical Letters 2020, 31, 2999-3000.
(9)Jinyang Chen, Yan Wu*, Cuicui Fu, Haiyan Cao, Xiaoping Tan, Wenbing Shi, Zhaoyang Wu. Ratiometric SERS biosensor for sensitive and reproducible detection of microRNA based on mismatched catalytic hairpin assembly. Biosensors and Bioelectronics 2019, 143, 111619.
(10)Yan Wu, Tingting Jiang, Zhaoyang Wu*, Ruqin Yu. Novel ratiometric surface-enhanced raman spectroscopy aptasensor for sensitive and reproducible sensing of Hg2+. Biosensors and Bioelectronics 2018, 99, 646-652.
(11)Yan Wu, Tingting Jiang, Zhaoyang Wu*, Ruqin Yu. Internal standard-based SERS aptasensor for ultrasensitive quantitative detection of Ag+ ion. Talanta 2018, 185, 30-36.
(12)Yan Wu, Fubing Xiao, Zhaoyang Wu*, Ruqin Yu. Novel Aptasensor Platform Based on Ratiometric Surface-Enhanced Raman Spectroscopy. Analytical Chemistry 2017, 89, 2852-2858.
(13)Yan Wu, Yongfang Sun, Fubing Xiao, Zhaoyang Wu*, Ruqin Yu. Sensitive inkjet printing paper-based colormetric strips for acetylcholinesterase inhibitors with indoxyl acetate substrate. Talanta 2017, 162, 174-179.
(14)Yan Wu*, Mengjie He, Honghui Zang, Junli Wang, Jing Li, Ting Yue, Rong Xu, Yueshan Jiang, Fang Zhao, Siyi Chen. Magnetic Fe NPs as Peroxidase Nanozyme for Sensitive and Rapid Colorimetric Monitoring of H2O2 and Xanthine. New Journal of Chemistry 2023, 47, 14630-14646.
(15)Yan Wu*, Jianmei Zhou, Yueshan Jiang, Wen Li, Mengjie He, Yao Xiao, Jinyang Chen. Silver nanoparticles@metal-organic framework as peroxidase mimics for colorimetric determination of hydrogen peroxide and blood glucose. Chinese Journal of Analytical Chemistry 2022, 50.12, 100187.
(16)易荣楠,吴燕*。表面增强拉曼光谱技术在microRNA检测中的研究进展。化学学报 2021, 79, 694-704.
(17)易荣楠,吴燕*,王俊力,赵芳,陈锦杨*。金属有机框架材料在表面增强拉曼光谱中的应用研究进展。分析化学 2023, 51, 147-159.
(18)吴燕,陈锦杨,付翠翠,石文兵。一种用于铅离子检测的CHA-SERS生物传感器及其制备方法和应用。中国,ZL 2020 1 0450097.1,2022. 10. 11。
(19)吴燕,陈锦杨,吴红谕,陈睿。一种基于1, 6-烯炔类化合物硝化/环化反应的新方法。中国,ZL 2019 1 0881998.3,2021. 05. 04。
(20)吴燕,陈锦杨,刘嘉陵,钟春涛。一种3-硝基-2-吲哚酮类化合物的制备方法。中国,ZL 2019 1 0974465.X,2020. 09. 29。